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. 1975 Mar;19(3):551-62.

Immunoglobulin synthesis and antibody content in the small intestine of the rabbit

J Menzel, D Rowley

Immunoglobulin synthesis and antibody content in the small intestine of the rabbit

J Menzel et al. Clin Exp Immunol. 1975 Mar.

Abstract

The concentration of immunoglobulin and specific antibody in the serum and the intestinal fluid and the rate of synthesis of immunoglobulin in the small intestine was measured in normal and immunized rabbits. IgA was found to be the predominant immunoglobulin in the intestinal fluid. IgA and IgG were secreted at rates of 4-3 mug/cm/hr and 1-3 mug/cm/hr respectively. Specific anti-Vibrio cholerae antibodies in the intestine were found mainly in the IgA class after oral immunization.

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