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Review
. 2002 May;2(5):389-96.
doi: 10.1038/nrc801.

A history of prostate cancer treatment

Samuel R Denmeade  1 , John T Isaacs
Affiliations
Review

A history of prostate cancer treatment

Samuel R Denmeade et al. Nat Rev Cancer. 2002 May.

Abstract

The increased incidence of prostate cancer has led to remarkable changes in diagnosis and treatment over the past century. What were the first ways in which prostate cancer was treated, and how did these evolve into the variety of therapeutic strategies from which patients have to choose today?

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Figures

Figure 1
Figure 1. Prostate cancer research pioneers
a | Charles Huggins discovered that prostate cancers respond to androgen therapy. b | Andrew Schally determined the structure of luteinizing hormone-releasing hormone and developed the means to synthesize it. c | Patrick Walsh developed a modified technique for radical retropubic prostatectomy. d | Malcolm Bagshaw investigated the use of radiation therapy for prostate cancer. e | Gerald Murphy evaluated the efficacy of chemotherapy in patients with hormone-refractory prostate cancer, and his lab discovered prostate-specific antigen.
Timeline
Timeline
A century of prostate cancer therapy
None
None
See this image and copyright information in PMC

References

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    1. Huggins C, Stephens RC, Hodges CV. Studies on prostatic cancer: 2. The effects of castration on advanced carcinoma of the prostate gland. Arch Surg. 1941;43:209.
    1. Palmer JF, editor. The Works of John Hunter F. R. S. with Notes. Longman; London: 1837.

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