[Sinonasal sarcoidosis: CT evaluation]

Abstract

Sarcoidosis uncommonly occurs in the sinonasal system and rarely in the absence of pulmonary disease. The mucosa of the septum and inferior turbinates are mostly affected. The diagnosis is based on endoscopic features, CT findings and finally the histologic appearance of non-caseating granulomas. The characteristic CT appearance consists of multiple mucosal nodules, mostly associated with various sinus fillings and inflammatory rhinitis. Septal perforation, nasal bone osteoporosis or destruction, cartilage destruction and saddle nose deformity can occur in patients with severe disease. However the diagnosis cannot be confirmed solely by CT and other causes of granulomatous inflammation have to be excluded using biopsy.