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Review
. 2002 Jun;106(2):127-38.
doi: 10.1046/j.1365-2567.2002.01447.x.

Qualitative differences between naïve and memory T cells

Marion Berard  1 , David F Tough
Affiliations
Review

Qualitative differences between naïve and memory T cells

Marion Berard et al. Immunology. 2002 Jun.
No abstract available

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Figures

Figure 1
Figure 1
Combined effects of qualitative and quantitative changes in memory T cells in mediating a rapid secondary response to infection. Effector memory T cells are situated in peripheral tissues at sites of pathogen entry. These cells exhibit effector function immediately upon recognition of antigen presented on non-professional APCs and limit the early spread of infection. Central memory T cells are activated in secondary lymphoid organs (i.e. the draining lymph node) following recognition of antigen on DCs and generate large numbers of effector cells. The response of central memory cells is prompt as a result of both a high frequency of antigen specific cells and their ability to differentiate rapidly into effectors.
See this image and copyright information in PMC

References

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