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. 2002 Jun;10(6):737-9.
doi: 10.1016/s0969-2126(02)00782-7.

HtrA--a renaissance protein

Catherine L Day  1 , Mark G Hinds
Affiliations
Free article

HtrA--a renaissance protein

Catherine L Day et al. Structure. 2002 Jun.
Free article

Abstract

Initially identified as proteases, members of the HtrA/DegP family of proteins have also been shown to act as chaperones in bacteria, and more recently implicated, as regulators of apoptosis in mammals. Two new structures of mammalian HtrA2 and E. coli DegP provide insights into the origin of this plurality of function.

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