This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

Review

. 2002 Jun 15;324(7351):1448-51.

doi: 10.1136/bmj.324.7351.1448.

Randomised trials in surgery: problems and possible solutions

Peter McCulloch¹, Irving Taylor, Mitsuru Sasako, Bryony Lovett, Damian Griffin

Affiliations

PMID: 12065273
PMCID: PMC1123389
DOI: 10.1136/bmj.324.7351.1448

Review

Randomised trials in surgery: problems and possible solutions

Peter McCulloch et al. BMJ. 2002.

. 2002 Jun 15;324(7351):1448-51.

doi: 10.1136/bmj.324.7351.1448.

Authors

Peter McCulloch¹, Irving Taylor, Mitsuru Sasako, Bryony Lovett, Damian Griffin

Affiliation

¹ Academic Unit of Surgery, University of Liverpool, Clinical Sciences Centre, University Hospital Aintree, Liverpool L9 7AL. petermcculloch@cs.com

PMID: 12065273
PMCID: PMC1123389
DOI: 10.1136/bmj.324.7351.1448

No abstract available

PubMed Disclaimer

Comment in

Randomised trials in surgery. Integrated approach is needed.
Madhok R, Handoll HH. Madhok R, et al. BMJ. 2002 Sep 21;325(7365):658. doi: 10.1136/bmj.325.7365.658/a. BMJ. 2002. PMID: 12242186 Free PMC article. No abstract available.
Randomised trials in surgery. Employment of academic and evidence based surgeons and epidemiologists may be the answer.
Bridgman S, Maffulli N. Bridgman S, et al. BMJ. 2002 Sep 21;325(7365):658. BMJ. 2002. PMID: 12269324 No abstract available.

Similar articles

Designing randomized clinical trials in surgery.
Lombardi R. Lombardi R. Br J Surg. 2014 Mar;101(4):293-5. doi: 10.1002/bjs.9323. Epub 2014 Jan 29. Br J Surg. 2014. PMID: 24477768 No abstract available.
Recruiting patients into randomized clinical trials in surgery.
Blazeby JM. Blazeby JM. Br J Surg. 2012 Mar;99(3):307-8. doi: 10.1002/bjs.7818. Epub 2012 Jan 11. Br J Surg. 2012. PMID: 22237652 No abstract available.
Recruiting patients into randomized clinical trials in surgery (Br J Surg 2012; 99: 307-308).
Jacobs WC, Kruyt MC, Oner FC. Jacobs WC, et al. Br J Surg. 2012 Aug;99(8):1164; author reply 1165. doi: 10.1002/bjs.8851. Br J Surg. 2012. PMID: 22777804 No abstract available.
Trials in surgery.
Lilford R, Braunholtz D, Harris J, Gill T. Lilford R, et al. Br J Surg. 2004 Jan;91(1):6-16. doi: 10.1002/bjs.4418. Br J Surg. 2004. PMID: 14716788 Review.
Randomized controlled trials of surgical interventions.
Farrokhyar F, Karanicolas PJ, Thoma A, Simunovic M, Bhandari M, Devereaux PJ, Anvari M, Adili A, Guyatt G. Farrokhyar F, et al. Ann Surg. 2010 Mar;251(3):409-16. doi: 10.1097/SLA.0b013e3181cf863d. Ann Surg. 2010. PMID: 20142732 Review.

See all similar articles

Cited by

Natural Experiments as a Study Method in Spinal Trauma Surgery: A Systematic Review.
Stadhouder A, van Rossenberg LX, Kik C, Muijs SPJ, Öner FC, Houwert RM. Stadhouder A, et al. Global Spine J. 2024 Jun;14(5):1640-1649. doi: 10.1177/21925682231220889. Epub 2023 Dec 11. Global Spine J. 2024. PMID: 38073538 Free PMC article. Review.
Evidence-Based Surgery: What Can Intra-Operative Images Contribute?
Regazzoni P, Jupiter JB, Liu WC, Fernández dell'Oca AA. Regazzoni P, et al. J Clin Med. 2023 Oct 27;12(21):6809. doi: 10.3390/jcm12216809. J Clin Med. 2023. PMID: 37959274 Free PMC article. Review.
Methodological and ethical quality of randomized controlled clinical trials in gastrointestinal surgery.
Bridoux V, Moutel G, Roman H, Kianifard B, Michot F, Herve C, Tuech JJ. Bridoux V, et al. J Gastrointest Surg. 2012 Sep;16(9):1758-67. doi: 10.1007/s11605-012-1952-0. Epub 2012 Jul 10. J Gastrointest Surg. 2012. PMID: 22777055
Examining the empirical evidence for IDEAL 2b studies: the effects of preceding prospective collaborative cohort studies on the quality and impact of subsequent randomized controlled trials of surgical innovations - protocol for a systematic review and case-control analysis.
Ibrahim M, Paez A, Yu J, Vasey B, Horovitz J, McCulloch P. Ibrahim M, et al. BMJ Surg Interv Health Technol. 2022 Nov 3;4(1):e000120. doi: 10.1136/bmjsit-2021-000120. eCollection 2022. BMJ Surg Interv Health Technol. 2022. PMID: 36353185 Free PMC article.
CUSUM: a tool for early feedback about performance?
Chang WR, McLean IP. Chang WR, et al. BMC Med Res Methodol. 2006 Mar 2;6:8. doi: 10.1186/1471-2288-6-8. BMC Med Res Methodol. 2006. PMID: 16509997 Free PMC article. Clinical Trial.

See all "Cited by" articles

References

1. Doll R. Summation of conference. Doing more good than harm: the evaluation of health care interventions. Ann N Y Acad Sci. 1994;703:313. - PubMed
1. Benson K, Harz AJ. A comparison of observational studies and randomised controlled trials. N Engl J Med. 2000;342:1878–1886. - PubMed
1. Concato J, Shah N, Horwitz RI. Randomised controlled trials, observational studies and the hierarchy of research designs. N Engl J Med. 2000;342:1887–1892. - PMC - PubMed
1. Pollock AV. The rise and fall of the random controlled trial in surgery. Theoretical Surgery. 1989;4:163–170.
1. Pollock AV. Surgical evaluation at the crossroads. Br J Surg. 1993;80:964–966. - PubMed

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
Medical
- ClinicalTrials.gov
- MedlinePlus Health Information