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. 1975 Mar 24;4(4):359-70.
doi: 10.1007/BF01732537.

Speculations on the origin and evolution of metabolism

H Hartman

Speculations on the origin and evolution of metabolism

H Hartman. J Mol Evol. .

Abstract

An autotrophic origin of metabolism is described, which requires clays, transition state metals, disulfide and dithiols, U.V. and cyanide ion. A general scheme is proposed, involving the fixation of CO2 and N2, for the evolution of intermediary metabolism based on the evolution of a complex system from a simple one. The basic conclusion is that metabolism could have evolved from a simple environment rather than from a complex one.

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References

    1. Bacteriol Rev. 1972 Jun;36(2):231-60 - PubMed
    1. Proc Natl Acad Sci U S A. 1966 Jun;55(6):1365-72 - PubMed
    1. Nature. 1965 Jan 23;205:328-40 - PubMed
    1. Biochem Biophys Res Commun. 1962 Jun 4;7:448-52 - PubMed
    1. Proc Natl Acad Sci U S A. 1945 Jun;31(6):153-7 - PubMed