doi: 10.1007/BF01257499.
[Oncobiograms and cancer chemotherapy: Hope or reality? (author's transl)]
[Article in
German]
- PMID: 1207291
- DOI: 10.1007/BF01257499
Item in Clipboard
[Oncobiograms and cancer chemotherapy: Hope or reality? (author's transl)]
[Article in
German]
Langenbecks Arch Chir.
1975 Nov.
Abstract
On the basis of animal experiments it is shown that the results of tumor chemotherapy can be predicted with the aid of in-vitro test systems. In investigations carried out on human tumors, the correlations obtained between in-vitro test results and response to therapy are promising. However, definitive proof of a correlation can only be provided by planned, statistically supported clinical studies. Two types of information can already be obtained from the in-vitro tests: data concerning the rate of proliferation of the tumor, on which the activity of cytostatic agents depends, and data on certain types of resistance to cytostatics.
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