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. 1975 Nov;30(2):273-8.

Sister chromatid exchanges--a sensitive assay of agents damaging human chromosomes

E Solomon, M Bobrow
  • PMID: 1207711

Sister chromatid exchanges--a sensitive assay of agents damaging human chromosomes

E Solomon et al. Mutat Res. 1975 Nov.

Abstract

Sister chromatid exchange frequencies in human lymphocyte chromosomes are greatly increased by alkylating agents, but ionizing radiation has little if any such effect. Scoring these exchanges may provide a useful technique for exploring the mechanisms of chromosome breakage and repair.

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