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Case Reports
. 2002 Jul;47(1):146-7.
doi: 10.1067/mjd.2002.120910.

Nail pigmentation caused by hydroxyurea: report of 9 cases

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Case Reports

Nail pigmentation caused by hydroxyurea: report of 9 cases

Nicola Aste et al. J Am Acad Dermatol. 2002 Jul.

Abstract

We report a series of 9 patients, 6 men and 3 women, who presented nail hyperpigmentation arising between 6 and 24 months from the start of hydroxyurea therapy. The most commonly observed clinical pattern was that of longitudinal melanonychia. In only 1 patient, who was affected in all 20 nails, we observed longitudinal melanonychia, diffuse melanonychia, and hyperpigmentation of the skin.

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