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Review
. 2002 Jul;61(7):580-7.
doi: 10.1136/ard.61.7.580.

Reactive arthritis or chronic infectious arthritis?

J Sibilia  1 , F-X Limbach
Affiliations
Review

Reactive arthritis or chronic infectious arthritis?

J Sibilia et al. Ann Rheum Dis. 2002 Jul.

Abstract

Microbes reach the synovial cavity either directly during bacteraemia or by transport within lymphoid cells or monocytes. This may stimulate the immune system excessively, triggering arthritis. Some forms of ReA correspond to slow infectious arthritis due to the persistence of microbes and some to an infection triggered arthritis linked to an extra-articular site of infection.

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Figures

Figure 1
Figure 1
The spectrum of arthritis induced by a bacterial infection. The host-bacterium interactions and, in particular, the bacterial virulence factors lead to different forms of arthritis. In some cases there may be no more than a simple "bystander" bacterial presence in the synovium.
Figure 2
Figure 2
Natural history of arthritogenic infections in reactive arthritis. See also Box 1.
See this image and copyright information in PMC

Comment in

References

    1. Lancet. 1973 Jul 21;2(7821):157 - PubMed
    1. Br J Vener Dis. 1973 Aug;49(4):376-80 - PubMed
    1. Br Med Bull. 1983 Apr;39(2):168-74 - PubMed
    1. Lancet. 1987 Jan 10;1(8524):72-4 - PubMed
    1. Arthritis Rheum. 1988 Aug;31(8):937-46 - PubMed

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