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Case Reports
. 2002 Jul 15;199(1-2):93-6.
doi: 10.1016/s0022-510x(02)00111-9.

Myoclonic involuntary movement associated with chronic manganese poisoning

Kenjiro Ono  1 , Kiyonobu Komai, Masahito Yamada
Affiliations
Case Reports

Myoclonic involuntary movement associated with chronic manganese poisoning

Kenjiro Ono et al. J Neurol Sci. .

Abstract

We report a 17-year-old man showing myoclonic involuntary movement (IVM) associated with chronic manganese (Mn) poisoning. The patient, a welder, showed myoclonic IVM mainly in the right upper and lower extremities, elevated levels of Mn in the blood and hair and high-intensity signals in the globus pallidus on T1-weighted MR images. Chelation therapy resulted in improvement of the myoclonic IVM and MRI abnormalities. This is the first report of Mn poisoning characterized by myoclonic IVM without parkinsonism.

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