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Review
. 2002 May 20;86(10):1529-33.
doi: 10.1038/sj.bjc.6600316.

Generation of dendritic cell-based vaccines for cancer therapy

G Reinhard  1 , A Märten, S M Kiske, F Feil, T Bieber, I G H Schmidt-Wolf
Affiliations
Review

Generation of dendritic cell-based vaccines for cancer therapy

G Reinhard et al. Br J Cancer. .

Abstract

Dendritic cells play a major role in the generation of immunity against tumour cells. They can be grown under various culture conditions, which influence the phenotypical and functional properties of dendritic cells and thereby the consecutive immune response mainly executed by T cells. Here we discuss various conditions, which are important during generation and administration of dendritic cells to elicit a tumouricidal T cell-based immune response.

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Figures

Figure 1
Figure 1
Schematic diagram of dendritic cell generation.
See this image and copyright information in PMC

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