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. 2002 Jul 1;87(1):70-4.
doi: 10.1038/sj.bjc.6600420.

Prognostic significance of immunohistochemically detected breast cancer node metastases in 218 patients

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Prognostic significance of immunohistochemically detected breast cancer node metastases in 218 patients

I de Mascarel et al. Br J Cancer. .

Abstract

Axillary lymph node metastases detected by immunohistochemistry in standard node-negative patients with breast carcinomas (13 out of 129 infiltrating ductal carcinomas and 37 out of 89 infiltrating lobular carcinomas) do not have any prognostic significance in patients followed up for a long time (respectively 24 and 18 years). Moreover, their pejorative significance in the literature is debatable since the groups and events taken into account are heterogeneous.

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Figures

Figure 1
Figure 1
Macroscopic lymph node processing. (A) Macroscopic serial sectioning. (B) Standard sectioning.
Figure 2
Figure 2
Metastasis-free survival according to presence or absence of node metastases detected by immunohistochemistry (IHM) in IDC group.
Figure 3
Figure 3
Metastasis-free survival according to presence or absence of node metastases detected by immunohistochemistry (IHM) in ILC group.

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References

    1. ByrneJWaldronRMcAvincheyDDervanP1987The use of monoclonal antibodies for the histopathological detection of mammary axillary micrometastases Eur J Surg Oncol 13409411 - PubMed
    1. ByrneJHorganPGEnglandSCallaghanJGivenHF1992A preliminary report on the usefulness of monoclonal antibodies to CA 15-3 and MCA in the detection of micrometastases in axillary lymph nodes draining primary breast carcinoma Eur J Cancer 28658660 - PubMed
    1. ChenZLWenDRCoulsonWFGiulianoAECochranAJ1991Occult metastases in the axillary lymph nodes of patients with breast cancer node negative by clinical and histologic examination and conventional histology Dis Markers 9239248 - PubMed
    1. CoteRJPetersonHFChaiwunBGelberRDGoldhirschACastiglione-GertschMGustersonBNevilleAM1999Role of immunohistochemical detection of lymph-node metastases in management of breast cancer. International Breast Cancer Study Group Lancet 354896900 - PubMed
    1. de MascarelIBonichonFCoindreJMTrojaniM1992Prognostic significance of breast cancer axillary lymph node micrometastases assessed by two special techniques: reevaluation with longer follow-up Br J Cancer 66523527 - PMC - PubMed