Integrins and prostate cancer metastases
- PMID: 12085969
- DOI: 10.1023/a:1015547830323
Integrins and prostate cancer metastases
Abstract
Integrins have emerged as modulators of a variety of cellular functions. They have been implicated in cell migration, survival, normal and aberrant cellular growth, differentiation, gene expression, and modulation of intracellular signal transduction pathways. In this review article, the structural and functional characteristics of integrins, their expression and their potential role in prostate cancer metastases will be discussed.
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