Review
doi: 10.1016/s0092-8674(02)00750-x.
Sex, AGility, and the regulation of alternative splicing
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- PMID: 12086596
- DOI: 10.1016/s0092-8674(02)00750-x
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Review
Sex, AGility, and the regulation of alternative splicing
Cell.
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Abstract
Alternative splicing is an important means of regulating the expression of eukaryotic genes and enhancing protein diversity. A detailed examination of the Drosophila Sex-lethal gene has led to two significant discoveries-the role of the splicing factor SPF45 in defining the site of exon ligation, and that alternative splicing can be regulated at the second step.
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