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Review
. 2002 Feb;1(1):19-30.
doi: 10.1016/s1535-6108(02)00024-7.

A matter of life and death

Douglas R Green  1 , Gerard I Evan
Affiliations
Free article
Review

A matter of life and death

Douglas R Green et al. Cancer Cell. 2002 Feb.
Free article

Abstract

We propose that deregulation of proliferation, together with a reduction in apoptosis, creates a platform that is both necessary and can be sufficient for cancer. The secondary traits of diverse neoplasms are a consequence of cell proliferation, tissue expansion, and other outcomes of this platform.

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