Radiologic findings of multiple myeloma with gastric involvement: a case report

Abstract

We report a case of multiple myeloma with gastric involvement occurring in a patient who underwent an upper gastrointestinal series (UGIS), CT and MRI. UGIS depicted a luminal protruding mass, while contrast-enhanced CT demonstrated marked thickening of the gastric wall, with subtle contrast enhancement. At T1- and T2-weighted MR imaging, the mass showed iso- and intermediate signal intensity, respectively. After the administration of contrast material, subtle homogeneous enhancement was apparent.

Fig. 1

Multiple myeloma with gastric involvement in a 61-year-old man. A. Upper gastrointestinal series shows a large, protruding, luminal mass (arrows) with a well-defined margin in the anterior wall of the gastric cardia. B. Contrast-enhanced CT scan demonstrates marked gastric wall thickening with subtle contrast enhancement (arrows). C. Axial T2-weighted image shows homogeneous signal intensity slightly higher than that of the liver (arrows). D. Axial gadolinium-enhanced MR image obtained 3 minutes after the administration of contrast material depicts homogeneous enhancement, similar to that of hepatic parenchyma. E. Photograph of endoscopic biopsy specimen shows dense and monotonous infiltration by plasma cells (original magnification, ×200; hematoxylin-eosin staining). Note the presence of a monomorphic population of plasma cells with variable atypia.