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Review
. 2002 Jun 29;324(7353):1570-6.
doi: 10.1136/bmj.324.7353.1570.

Risk factor thresholds: their existence under scrutiny

M R Law  1 , N J Wald
Affiliations
Review

Risk factor thresholds: their existence under scrutiny

M R Law et al. BMJ. .
No abstract available

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Figures

Figure 1
Figure 1
Incidence (95% confidence interval) of ischaemic heart disease according to diastolic blood pressure (top), serum cholesterol (centre), and body mass index (bottom). Data from cohort studies; incidence (vertical axes) plotted on arithmetic scale (left hand plots) and proportional (or logarithmic) scale (right hand plots)
Figure 2
Figure 2
Incidence (95% confidence interval) of stroke according to diastolic blood pressure, diabetes (non-insulin independent) according to body mass index, neural tube defects according to maternal plasma folate, and hip fracture according to bone mineral density. Data from cohort studies; incidence (vertical axes) plotted on arithmetic scale (left hand plots) and proportional (or logarithmic) scale (right hand plots)
Figure 3
Figure 3
Implication of straight line dose-response relations according to use of arithmetic or logarithmic scales
Figure 4
Figure 4
Straight line relation between serum cholesterol and ischaemic heart disease (as for serum cholesterol in fig 1) and explanation to account for straight line being cause and effect across upper portion of serum cholesterol distribution (where it has been confirmed by randomised trials) but not across the lower portion
See this image and copyright information in PMC

Comment in

References

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