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Comparative Study
. 2002 Jul;40(7):2594-7.
doi: 10.1128/JCM.40.7.2594-2597.2002.

Differences between Staphylococcus aureus isolates from medical and nonmedical hospital personnel

Christian Cespedes  1 , Maureen Miller, Bianca Quagliarello, Peter Vavagiakis, Robert S Klein, Franklin D Lowy
Affiliations
Comparative Study

Differences between Staphylococcus aureus isolates from medical and nonmedical hospital personnel

Christian Cespedes et al. J Clin Microbiol. 2002 Jul.

Abstract

It is unclear whether the levels of Staphylococcus aureus colonization of hospital personnel with patient exposure are increased or whether personnel become colonized with more antibiotic-resistant strains. Differences in nasal and hand carriage of S. aureus between medical and nonmedical hospital personnel were examined. No differences in nasal carriage between the two groups were found; however, there was a trend that suggested differences in the rates of hand carriage of S. aureus (18% of nonmedical personnel and 10% of medical personnel). Medical personnel were colonized with more antibiotic-resistant isolates than nonmedical personnel (mean, 2.8 versus 2.1 isolates [P < 0.03]), and the strain profiles indicated that they tended to be more clonal in origin, suggesting that exposure to hospital isolates alters the colonization profile.

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Figures

FIG. 1.
FIG. 1.
Dendrograms illustrating the relationship of S. aureus nasal isolates collected from MP (A) and NMP (B) and analyzed by PFGE. The right-hand sides of panels A and B illustrate the PFGE patterns for the individual isolates. The isolates were compared by use of the DC. Strains that were ≥70% similar were classified as related. One isolate from a member of the MP was unavailable for PFGE. Two isolates were from a single subject who was a member of the NMP. Note that the scales of the two panels differ.
See this image and copyright information in PMC

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