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. 2002 Jul;40(7):2622-5.
doi: 10.1128/JCM.40.7.2622-2625.2002.

Virulence genes in Helicobacter pylori strains from West Bengal residents with overt H. pylori-associated disease and healthy volunteers

Santanu Chattopadhyay  1 , Simanti Datta, Abhijit Chowdhury, Sujit Chowdhury, Asish K Mukhopadhyay, K Rajendran, S K Bhattacharya, Douglas E Berg, G Balakrish Nair
Affiliations

Virulence genes in Helicobacter pylori strains from West Bengal residents with overt H. pylori-associated disease and healthy volunteers

Santanu Chattopadhyay et al. J Clin Microbiol. 2002 Jul.

Abstract

We compared putative molecular markers of virulence (vacA, cagA, and iceA) of Helicobacter pylori strains isolated from 52 adult duodenal ulcer patients from West Bengal, India, with those of H. pylori strains isolated from 48 adult healthy volunteers from the same region. On the basis of genotyping by PCR, we conclude that the H. pylori strains isolated from the two study groups were indistinguishable and that there are geographic variations in the association of certain putative H. pylori virulence genes with clinical status.

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Figures

FIG. 1.
FIG. 1.
Combinations of vacA, cagA, and iceA genotypes of H. pylori strains isolated from DU patients and HVs. +, positive for the gene; −, negative for the gene.
See this image and copyright information in PMC

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