Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2002 Jul;9(4):753-62.
doi: 10.1128/cdli.9.4.753-762.2002.

Evaluation of events occurring at mucosal surfaces: techniques used to collect and analyze mucosal secretions and cells

Affiliations
Review

Evaluation of events occurring at mucosal surfaces: techniques used to collect and analyze mucosal secretions and cells

Bruno Guy. Clin Diagn Lab Immunol. 2002 Jul.
No abstract available

PubMed Disclaimer

Figures

FIG. 1.
FIG. 1.
Cells and soluble factors present within mucosal tissues and secretions. Cellular analyses are performed mostly on material coming from biopsies or surgery, while soluble mediators (antibodies, cytokines, and chemokines) are preferentially measured in secretions. Some cells may also be present in the lumen, and their proportion may be higher under certain physiological conditions (the hormonal cycle in genital tissues) or pathological conditions (inflammation or rupture of epithelium integrity by pathogens). NK, natural killer cells; IELs, intraepithelial lymphocytes; Mφ, macrophages; SC, secretory component; PMNs, polymorphonuclear leukocytes; IL, interleukin; TGFβ, transforming growth factor β; IFNγ, gamma interferon.

Similar articles

Cited by

References

    1. Ahlstedt, I., C. Lindholm, H. Lönroth, A. Hamlet, A. M. Svennerholm, and M. Quinding-Järbrink. 1999. Role of local cytokines in increased gastric expression of the secretory component in Helicobacter infection. Infect. Immun. 67:4921-4925. - PMC - PubMed
    1. Asanuma, H., C. Aizawa, T. Kurata, and S. Tamura. 1998. IgA antibody forming cell responses in the NALT of mice vaccinated by intranasal, intravenous and/or subcutaneous administration. Vaccine 16:1257-1263. - PubMed
    1. Aufricht, C., W. Tenner, H. R. Salzer, A. E. Khoss, E. Wurst, and K. Herkner. 1992. Salivary IgA concentration is influenced by the saliva collection method. Eur. J. Clin. Chem. Clin. Biochem. 30:81-83. - PubMed
    1. Bamford, K. B., X. Fan, S. E. Crowe, J. F. Leary, W. K. Gourley, G. K. Luthra, E. G. Brooks, D. Y. Graham, V. E. Reyes, and P. B. Ernst. 1998. Lymphocytes in the human gastric mucosa during Helicobacter pylori have a Th1 phenotype. Gastroenterology 114:482-492. - PubMed
    1. Bomsel, M., M. Heyman, H. Hocini, S. Lagaye, L. Belec, C. Dupont, and C. Desgranges. 1998. Intracellular neutralization of HIV transcytosis across tight epithelial barriers by anti-HIV envelope protein dIgA or IgM. Immunity 9:277-287. - PubMed

LinkOut - more resources