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Case Reports
. 2002 Jul-Aug;10(4):476-8.

Valproate-induced hyperammonemia as a cause of altered mental status

Denise Feil  1 , Kenneth Chuang, David L Sultzer
Affiliations
  • PMID: 12095907
Case Reports

Valproate-induced hyperammonemia as a cause of altered mental status

Denise Feil et al. Am J Geriatr Psychiatry. 2002 Jul-Aug.

Abstract

The authors describe valproate-induced hyperammonemia and mental status changes in an 88-year-old man, the first known reported case in an elderly patient. They discuss this underrecognized complication of valproate use and the implications for treating elderly patients, in whom valproate use is increasing.

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