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Comment
. 2002 Jul 1;542(Pt 1):61-2.
doi: 10.1113/jphysiol.2002.013328.

The presence of local osmotic gradients can account for the water flux driven by the Na+-glucose cotransporter

Jean-Yves Lapointe  1 , Marilène Gagnon, Simon Poirier, Pierre Bissonnette
Affiliations
Comment

The presence of local osmotic gradients can account for the water flux driven by the Na+-glucose cotransporter

Jean-Yves Lapointe et al. J Physiol. .
No abstract available

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Figures

Figure 1
Figure 1. Effect of a rapid reduction in cotransport current on the observed cell swelling
Superimposed onto the four experimental recordings are the predictions from the water cotransport model (dashed line) and from the osmolyte accumulation model (continuous line).
Figure 2
Figure 2. Cotransport-stimulated cell swelling
The continuous smooth line represents the fit provided by the diffusion model using the parameters described in the text. The inset shows the osmolarity profiles from the centre of the oocyte to the plasma membrane as a function of time after initiating the cotransport current.
See this image and copyright information in PMC

Comment on

  • Water pumps.
    Loo DD, Wright EM, Zeuthen T. Loo DD, et al. J Physiol. 2002 Jul 1;542(Pt 1):53-60. doi: 10.1113/jphysiol.2002.018713. J Physiol. 2002. PMID: 12096049 Free PMC article. Review.

References

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    1. Loo DD, Zeuthen T, Chandy G, Wright EM. Proceedings of the National Academy of Sciences of the USA. 1996;93:13367–13370. - PMC - PubMed
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    1. Zeuthen T, Meinild A, Klaerke DA, Loo DD, Wright EM, Belhage B, Litman T. Biology of the Cell. 1997;89:307–312. - PubMed

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