Thalidomide, an antiangiogenic agent with clinical activity in cancer
- PMID: 12109812
- DOI: 10.1016/s0753-3322(02)00177-4
Thalidomide, an antiangiogenic agent with clinical activity in cancer
Abstract
Despite the teratogenic past of thalidomide, there is recent evidence indicating the drug's efficacy in the management of various diseases from immune disorders to cancers. The history, pharmacodynamic and pharmacokinetic properties of thalidomide in the clinic are discussed in this review article.
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