How to grab a microtubule on the move
- PMID: 12110160
- DOI: 10.1016/s1534-5807(02)00209-5
How to grab a microtubule on the move
Abstract
In migrating cells, Rho family GTPases and their effectors play a central role in polarizing and in organizing the actin and microtubule cytoskeletons. A study by Fukata et al. in the June 28th issue of Cell now shows that the Rac1/Cdc42 effector IQGAP1 captures microtubules by binding to CLIP170.
Comment on
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Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170.Cell. 2002 Jun 28;109(7):873-85. doi: 10.1016/s0092-8674(02)00800-0. Cell. 2002. PMID: 12110184
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