Top-SUMO wrestles centromeric cohesion
- PMID: 12110161
- DOI: 10.1016/s1534-5807(02)00214-9
Top-SUMO wrestles centromeric cohesion
Abstract
Sister chromatid cohesion at the centromere is distinct from cohesion at the chromosome arms. In the June issue of Molecular Cell, Bachant et al. have shown that centromeric cohesion in budding yeast is specifically regulated by SUMO-1 modification of Topoisomerase II.
Comment on
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CLIP170-like tip1p spatially organizes microtubular dynamics in fission yeast.Cell. 2000 Sep 1;102(5):695-704. doi: 10.1016/s0092-8674(00)00091-x. Cell. 2000. PMID: 11007487
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