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Review
. 2002 Jun 28;109(7):801-6.
doi: 10.1016/s0092-8674(02)00798-5.

Histone methylation: dynamic or static?

Andrew J Bannister  1 , Robert Schneider, Tony Kouzarides
Affiliations
Free article
Review

Histone methylation: dynamic or static?

Andrew J Bannister et al. Cell. .
Free article

Abstract

Methylation of histones mediates transcriptional silencing at heterochromatin sites and affects regulated transcription at euchromatic loci. So is the methyl group a permanent mark on histones, or can it be removed by an active process necessary for regulated gene expression?

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