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. 1975 Oct;5(4):371-3.
doi: 10.1007/BF02205245.

Effect of calcitonin on carrageenan foot oedema

Effect of calcitonin on carrageenan foot oedema

S E Abdullahi et al. Agents Actions. 1975 Oct.

Abstract

The effect of salmon calcitonin (SCT) on acute inflammation was tested in carrageenan induced foot oedema of the rat. A considerable inhibition of the oedema was obtained with 20 MRC U/kg of SCT. The injection of SCT is followed by decrease of calcemia. A hypothesis of possible inhibition of prostaglandin (PG) synthesis and/or release, caused by decrease of calcemia, is advanced.

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