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. 1979 Nov;17(11):717-9.
doi: 10.1515/cclm.1979.17.11.717.

Influence of Ca2+ ions and cation chelators on activity measurement of creatine kinase isoenzymes

K Jung, R Neumann, W Liese, E Egger

Influence of Ca2+ ions and cation chelators on activity measurement of creatine kinase isoenzymes

K Jung et al. J Clin Chem Clin Biochem. 1979 Nov.

Abstract

EDTA and EGTA, added to the reaction mixture for the activity determination of creatine kinase, stimulate the activity of creatine kinase to various extents by suppressing the inhibitory effect of Ca2+ ions. The activation effect is highest for isoenzyme BB, less for isoenzyme MB, and lowest for isoenzyme MM.

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