Review
Apoptosis: target of cancer therapy
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- PMID: 12114400
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Review
Apoptosis: target of cancer therapy
Clin Cancer Res.
2002 Jul.
Abstract
Recent knowledge on apoptosis has made it possible to devise novel approaches, which exploit this process to treat cancer. In this review, we discuss in detail approaches to induce tumor cell apoptosis, their mechanism of action, stage of development, and possible drawbacks. Finally, the obstacles yet to be overcome and the perspectives for potential clinical use of apoptosis-triggering approaches in cancer therapy in the future are assessed.
Comment in
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Correspondence re: C. G. Ferreira et al., Apoptosis: target of cancer therapy. Clin. Cancer Res., 8: 2024-2034, 2002.Clin Cancer Res. 2003 Feb;9(2):912; author reply 913. Clin Cancer Res. 2003. PMID: 12576467 No abstract available.
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