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Review
. 2002 Aug;88(2):198-202.
doi: 10.1136/heart.88.2.198.

Heart failure in the young

Michael Burch  1
Affiliations
Review

Heart failure in the young

Michael Burch. Heart. 2002 Aug.
No abstract available

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Figures

Figure 1
Figure 1
Survival curve (blue line) from presentation of 63 children with dilated cardiomyopathy, with 95% confidence intervals (red and green lines). Reproduced from Burch et al with permission from the BMJ Publishing Group.
Figure 2
Figure 2
Histological sample from an explanted heart of a 15 year old girl who presented with new onset heart failure and required ECMO (extracorporeal membrane oxygenation) bridge to transplant. Histology shows lymphocytic infiltration with giant cell formation— giant cell myocarditis. The patient remains well at follow up. Slide provided by Dr Marian Malone from the pathology department at Great Ormond Street Hospital for Children.
Figure 3
Figure 3
Multistate survival curves for 346 consecutive acute lymphoblastic leukaemia and Wilms' tumour patients treated with anthracycline between 1971 and 1990, identifying non-cardiac deaths and cardiac problems (fractional shortening h 25%). Adapted from Sorenson et al.
See this image and copyright information in PMC

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References

    1. Burch M, Siddiqi SA, Celermajer DS, et al. Dilated cardiomyopathy in children: determinants of outcome. Br Heart J 1994;72:246–250. ▸ This is a review of outcome in dilated cardiomyopathy in children in the UK. The data are useful but are becoming out of date. - PMC - PubMed
    1. Kamisago M, Sharma SD, DePalma SR, et al. Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy. N Engl J Med 2000;343:1688–96. ▸ An interesting genetic paper that shows evidence for mutations causing dilated cardiomyopathy in different sarcomere proteins. - PubMed
    1. Mason JW, O'Connell JB, Herskowitz A, et al. A clinical trial of immunosuppressive therapy for myocarditis. The myocarditis treatment trial investigators. N Engl J Med 1995;333:269–75. - PubMed
    1. McCarthy RE, Boehmer JP, Hruban RH, et al. Long-term outcome of fulminant myocarditis as compared with acute (nonfulminant) myocarditis. N Engl J Med 2000;342:690–5. - PubMed
    1. Stiller B, Dahnert I, Weng YG, et al. Children may survive severe myocarditis with prolonged use of biventricular assist devices. Heart 1999;82:237–40. - PMC - PubMed