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. 2002 May;34(5):339-42.
doi: 10.1016/s1590-8658(02)80127-x.

Cancer surveillance in ulcerative colitis: critical analysis of long-term prospective programme

G Biasco  1 , F P Rossini, R Hakim, G Brandi, M Di Battista, G Di Febo, C Calabrese, R Santucci, M Miglioli
Affiliations

Cancer surveillance in ulcerative colitis: critical analysis of long-term prospective programme

G Biasco et al. Dig Liver Dis. 2002 May.

Abstract

Background: Patients with longstanding ulcerative colitis are at increased risk of colorectal cancer. In the literature, no agreement has yet been reached regarding prevention strategies. Our report sums up a prospective study started in 1980.

Methods: A total of 65 patients affected by ulcerative colitis for more than seven years were admitted to a regular colonoscopic and biopsy follow-up programme.

Results: Some 20 years after the beginning of the study, 23 (35.3%) patients have been operated upon, 2 patients have died but not from cancer 29 (44.66%) patients have abandoned the programme. Only 11 (16.9%) patients have remained under colonoscopic surveillance.

Conclusion: These results cast some doubts on the significance of such a programme and on its long-term feasibility.

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