[Vascularization of tumors of the mammary glands]

Abstract

The study of peculiarities of the blood supply of pre-tumour foci and cancer tumours of mammary glands of humans and mice of highly cancerous strains "A" and "C3H" by means of injectional, histological, histo- and enzymochemical and electron microscopical methods has shown that vascularization of corresponding zones alters with development of pre-cancerous growings in mammary glands. The most pronounced alterations are observed in the vessels of cancer tumours depending on the developmental stage, histological structure and differentiation degree. Changes in the character of "angioplastic" reaction, ultrastructural and histochemical reorganization of the vascular wall explain the peculiarities of microvascularization and metastazing of cancer.