doi: 10.1111/j.1365-2141.1975.tb00831.x.
Distribution of fibrinogen, and platelet factors 4 and XIII in subcellular fractions of human platelets
- PMID: 1212435
- DOI: 10.1111/j.1365-2141.1975.tb00831.x
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Distribution of fibrinogen, and platelet factors 4 and XIII in subcellular fractions of human platelets
Br J Haematol.
1975 Sep.
Abstract
The distribution of fibrinogen, platelet factor 4 (heparin-neutralizing factor) and factor XIII amongst subcellular fractions of human platelets was determined. It was found that fibrinogen and platelet factor 4 peaked sharply in the region of the density gradient previously shown to be heavily enriched with alpha-granules. By contrast, factor XIII, fibrin-stabilizing factor, was found exclusively in the supernatant.
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