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Case Reports
. 2002 Jul-Aug;6(4):614-6.
doi: 10.1016/s1091-255x(01)00006-3.

Breast cancer masquerading as a primary gastric carcinoma

Francine Tremblay  1 , Bruce Jamison, Sarkis Meterissian
Affiliations
Case Reports

Breast cancer masquerading as a primary gastric carcinoma

Francine Tremblay et al. J Gastrointest Surg. 2002 Jul-Aug.

Abstract

The differentiation between primary gastric cancer and a metastatic breast tumor to the stomach is important for planning of treatment and to spare the patient unnecessary surgery. We report a rare case of breast cancer with metastasis to the stomach. The diagnosis was established by histologic and immunohistochemical analyses of biopsies of the stomach lesion using gross cystic disease fluid protein-15, cytokeratin, carcinoembryonic antigen, and epithelial membrane antigen. Positivity for gross cystic disease fluid protein-15 with negative staining for carcinoembryonic antigen supported the diagnosis of a breast cancer metastasis. The patient was treated with systemic chemotherapy without surgery and is still alive 2 years after initial referral for a gastric neoplasm.

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