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. 2002 Aug;81(3):337-42.
doi: 10.1016/s0378-8741(02)00116-2.

Anticancer and antithrombin activity of Russian plants

Elena A Goun  1 , V M Petrichenko, S U Solodnikov, T V Suhinina, Martin A Kline, Glenn Cunningham, Chi Nguyen, Howard Miles
Affiliations

Anticancer and antithrombin activity of Russian plants

Elena A Goun et al. J Ethnopharmacol. 2002 Aug.

Abstract

A chromogenic bioassay was utilized to determine the antithrombin activity of the methylene chloride and methanol extracts prepared from forty-five plants of Russia. Mouse leukemia cells (L1210) were utilized to screen these extracts for activity against cancer. The results indicated that eight plant extracts demonstrated 90% or higher activity in the inhibition of thrombin. Also, nine methanol extracts demonstrated activity of 90% or higher in the inhibition of mouse leukemia L1210 cells. The methanol extracts of Quercus robur and Sanguisorba officinalis demonstrated high activity against both thrombin and cancer.

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