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Review
. 2002 Aug;21(6):608-9.
doi: 10.1097/00003226-200208000-00016.

Keratopathy from congenital syphilis

Affiliations
Review

Keratopathy from congenital syphilis

Seenu M Hariprasad et al. Cornea. 2002 Aug.

Abstract

Purpose: Therapeutic decision-making in syphilitic corneal disease is discussed after seeing a patient with keratopathy from congenital syphilis.

Methods: Case report and review of the literature.

Results: Laboratory evaluation of our patient revealed a nonreactive serum rapid plasma reagin (RPR) test and a positive microhemagglutination assay-Treponema pallidum (MHA-TP) test.

Conclusion: Any patient with residual interstitial keratopathy, especially if bilateral, should be suspected to have congenital syphilis if the patient or parents were ever treated for a sexually transmitted disease, if stigmata of congenital syphilis are present, or if childhood ocular inflammation occurred.

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