[Coexistence of pure red cell aplasia and autoimmune hemolytic anemia occurring during remission of malignant lymphoma]

Abstract

A 56-year-old woman was admitted because of anemia in April 2001. A diagnosis of malignant lymphoma (ML) (diffuse mixed, B-cell type) had been made in March 2000 whereafter she had been treated with CHOP chemotherapy and had achieved complete remission (CR). On examination, it was found she had concurrently developed pure red cell aplasia (PRCA) and warm type autoimmune hemolytic anemia (AIHA) without relapse of the ML. The PRCA and AIHA were successfully treated with prednisolone. To our knowledge, only 4 cases of PRCA and AIHA associated with ML have been reported. Moreover, this is the first report of the coexistence of PRCA and AIHA occurring during the CR of ML.