doi: 10.1159/000301532.
Experimental production of aneuploidy in mouse oocytes
- PMID: 1213601
- DOI: 10.1159/000301532
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Experimental production of aneuploidy in mouse oocytes
Gynecol Invest.
1975.
Abstract
The normal course of meiosis can be interrupted in cultured mouse oocytes by exposre to low temperature (23 degrees C). Re-transfer of the oocytes to a 37 degrees C environment will permit the meiotic process to resume and progress as usual to second metaphase. However, a significant number of oocytes treated in this manner prove to contain abnormal numbers of chromosomes.
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