Review
doi: 10.1152/nips.01387.2002.
New disguises for an old channel: MaxiK channel beta-subunits
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- PMID: 12136044
- DOI: 10.1152/nips.01387.2002
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Review
New disguises for an old channel: MaxiK channel beta-subunits
News Physiol Sci.
2002 Aug.
Abstract
Ca(2+)-activated K(+) channels of large conductance (MaxiK or BK channels) control a large variety of physiological processes, including smooth muscle tone, neurosecretion, and hearing. Despite being coded by a single gene (Slowpoke), the diversity of MaxiK channels is great. Regulatory b-subunits, splicing, and metabolic regulation create this diversity fundamental to the adequate function of many tissues.
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