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Case Reports
. 2002 Jun;27(4):277-9.
doi: 10.1046/j.1365-2230.2002.01020.x.

Steroid responsive cutaneous Rosai-Dorfman disease associated with uveitis and hypothyroidism

A Salim  1 , M Williamson, F Barker, J Hughes
Affiliations
Case Reports

Steroid responsive cutaneous Rosai-Dorfman disease associated with uveitis and hypothyroidism

A Salim et al. Clin Exp Dermatol. 2002 Jun.

Abstract

We report a patient with steroid responsive cutaneous Rosai-Dorfman disease (RDD) associated with bilateral anterior uveitis and hypothyroidism. RDD is a rare histiocytic disorder of unknown aetiology. There is characteristic histology in which large pale-staining histiocytes exhibit emperipolesis and stain positive for S-100 protein. This condition is thought to be a reactive process rather than a neoplastic one and viral and immune mediated causes have been postulated.

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