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Case Reports
. 2002 Aug;47(2):311-3.

Autoimmune progesterone dermatitis manifested as erythema annulare centrifugum: Confirmation of progesterone sensitivity by in vitro interferon-gamma release

Sima Halevy  1 , Arnon D Cohen, Eitan Lunenfeld, Nili Grossman
Affiliations
  • PMID: 12140482
Case Reports

Autoimmune progesterone dermatitis manifested as erythema annulare centrifugum: Confirmation of progesterone sensitivity by in vitro interferon-gamma release

Sima Halevy et al. J Am Acad Dermatol. 2002 Aug.

Abstract

Autoimmune progesterone dermatitis was manifested as deep-type erythema annulare centrifugum. Sensitivity to progesterone was studied in vivo by means of intradermal and patch tests, which revealed immediate-type and delayed-type hypersensitivity, respectively. Sensitivity to progesterone was further confirmed in vitro by results of an interferon-gamma release test, which imply a possible role for T(H)1-type cytokines in autoimmune progesterone dermatitis.

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