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Review
. 2002 Jul;18(3):619-41, viii.
doi: 10.1016/s0749-0704(02)00005-2.

Endocrine and metabolic issues in the management of the chronically critically ill patient

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Review

Endocrine and metabolic issues in the management of the chronically critically ill patient

Jeffrey I Mechanick et al. Crit Care Clin. 2002 Jul.

Abstract

The metabolic syndrome of chronic critical illness (CCI) consists of multisystem organ dysfunction resulting from the initial acute injury and chronic immune-neuroendocrine axis activation, adult kwashiorkor-like malnutrition, and prolonged immobilization with suppression of the PTH-vitamin D axis and hyper-resorptive metabolic bone disease. CCI patients can also present unique challenges in the management of diabetes mellitus, thyroid and adrenal diseases, electrolyte abnormalities and hypogonadism.

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