Comment
doi: 10.1126/science.1075456.
Checking that replication breakdown is not terminal
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- PMID: 12142525
- DOI: 10.1126/science.1075456
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Comment
Checking that replication breakdown is not terminal
Science.
.
Abstract
Two new studies help to clarify the relationship between checkpoint proteins, recombination, and replication fork integrity.
Comment on
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Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects.Science. 2002 Jul 26;297(5581):599-602. doi: 10.1126/science.1074023. Science. 2002. PMID: 12142537
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ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.Science. 2002 Jul 26;297(5581):602-6. doi: 10.1126/science.1071398. Science. 2002. PMID: 12142538
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