The effect of fluoride and hypothermia on the in vitro metabolism of mivacurium
- PMID: 12145059
- DOI: 10.1097/00000539-200208000-00029
The effect of fluoride and hypothermia on the in vitro metabolism of mivacurium
Abstract
The fluoride inhibition of mivacurium hydrolysis by pseudocholinesterase increases in hypothermia, but it will very rarely occur in clinical practice because it requires rather large fluoride concentrations (>50 micromol/L) and very low temperatures (<28 degrees C).
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