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Case Reports
. 2002 Aug;40(8):3071-5.
doi: 10.1128/JCM.40.8.3071-3075.2002.

Corneal ulcer caused by the new fungal species Sarcopodium oculorum

Josep Guarro  1 , Ana Luisa Höfling-Lima, Josepa Gené, Denise De Freitas, Patricio Godoy, Maria Luisa Zorat-Yu, Luis Zaror, Olga Fischman
Affiliations
Case Reports

Corneal ulcer caused by the new fungal species Sarcopodium oculorum

Josep Guarro et al. J Clin Microbiol. 2002 Aug.

Abstract

We describe a case of keratitis caused by a new species of the hyphomycetous genus Sarcopodium, S. oculorum. The corneal ulcer developed after 5 months of treatment with corticosteroids in a Brazilian boy diagnosed with allergic conjunctivitis. Fungal hyphae and conidia were detected in corneal scrapings, and repeated cultures were positive for this fungus. The infection was resolved with natamycin and ketoconazole. Eleven antifungals were tested against this fungus, and all except flucytosine and fluconazole showed in vitro activity.

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Figures

FIG. 1.
FIG. 1.
(A) Corneal ulcer. (B) Gram stain showing segmented hyphae and conidia (arrows). Magnification, ×1,280.
FIG. 2.
FIG. 2.
S. oculorum IMI 387421. (A and B) Sporodochia. (C to E) Conidiophores and conidia from sporodochia. (F) Undifferentiated hyphae with conidiogenous cells and conidia.
FIG. 3.
FIG. 3.
S. oculorum IMI 387421. (A and B) Sporodochia from the colony growing on PDA after 3 weeks of incubation at 25°C. (C) Sporodochium with setae (arrows). (D and E) Conidiophores from sporodochia. (F) Part of a sporodochium showing setae (arrows) among conidiophores. (G) Conidia from sporodochia. (H) Conidia from undifferentiated hyphae. Magnifications: ×120 (A), ×400 (B), ×200 (C), ×2,130 (D), ×3,010 (E), ×600 (F), and ×4,000 (G and H).
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References

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