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Review
. 2002 Aug;57(8):736-41.
doi: 10.1136/thorax.57.8.736.

Chronic obstructive pulmonary disease. 1: Susceptibility factors for COPD the genotype-environment interaction

A J Sandford  1 , E K Silverman
Affiliations
Review

Chronic obstructive pulmonary disease. 1: Susceptibility factors for COPD the genotype-environment interaction

A J Sandford et al. Thorax. 2002 Aug.

Abstract

Genetic factors including alpha(1)-antitrypsin deficiency are important in COPD. Candidate gene association studies in COPD are reviewed. Efforts to identify interactions between genetic factors and environmental determinants such as smoking may lead to improved understanding of the pathogenesis of the disease.

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