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Comment
. 2002 Jul;2(1):1-2.
doi: 10.1016/s1535-6108(02)00087-9.

A mitochondrial Achilles' heel in cancer?

David M Hockenbery  1
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A mitochondrial Achilles' heel in cancer?

David M Hockenbery. Cancer Cell. 2002 Jul.
Free article

Abstract

Mitochondria are principal actors in apoptosis as central hubs for diverse apoptotic signals. A new paper demonstrates the therapeutic potential of directly engaging these apoptotic pathways by identifying a mitochondrial toxin selective for tumor cells.

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