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. 1995 Nov;2(4):388-391.

Human rotavirus subgroups and severity of associated diarrhoea in Ghana

George E. Armah  1 , Hiroki Hori, Akwasi Anyanful, Julius A. Addo, Joseph O. Commey, Hitoshi Kamiya, Francis K. Nkrumah
Affiliations
  • PMID: 12160428

Human rotavirus subgroups and severity of associated diarrhoea in Ghana

George E. Armah et al. Afr J Health Sci. 1995 Nov.

Abstract

In a 12 month study of children with acute diarrhoea seeking medical care in 2 hospitals in Accra, Ghana, 16.3% were found to be infected with human rotaviruses (HRV). Vomiting and diarrhoea were the main symptoms observed. HRV infection was frequently associated with severe diarrhoea. Vomiting was however less frequent in HRV associated diarrhoea than in non HRV diarrhoea. No significant association was observed between the severity of dehydration and HRV infection. Subgroup II HRV was the predominant subgroup identified with the dominant serotypes being HRV serotypes 1 and 4. Poly-acrylamide gel electrophoresis of HRV RNAs isolated from 40 positive stool samples revealed the existence of 7 distinct electrophoretic migration patterns in the study population.

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